The Correlation Between Sleep Disturbances and Depression in Type 2 Diabetes

In a study, researchers compared severity of sleep disturbances in patients with type 2 diabetes (n=107) versus patients with pre-diabetes (n=48) and healthy individuals (n=154), as well as further explored whether depressive symptoms affect the relationship between sleep disturbances and  type 2 diabetes. Severity of depressive symptoms was measured using the Beck Depression Inventory‐II, and sleep disturbances were measured using the Mini Sleep Questionnaire. A mediation analysis was conducted to determine if the depressive symptoms were associated with sleep disturbances and type 2 diabetes. Patients with type 2 diabetes were more likely to have depressive symptoms and higher levels of insomnia, hypersomnia, and overall sleep disturbances compared with healthy individuals and patients with prediabetes; there were no differences in these outcomes between healthy individuals and patients with prediabetes. A correlation was observed between sleep disturbances and severity of depressive symptoms. When controlling for confounders, severity of sleep disturbances and severity of depressive symptoms were both predictive of type 2 diabetes. There was no significant association between sleep disturbances and type 2 diabetes, but depressive symptoms mediated the correlation between sleep disturbances and type 2 diabetes.