CTA and Invasive Coronary Angiography Similar to SPECT for Predicting Revascularization

This study, looking at the diagnostic accuracy of 320—slice CTA for obstructive coronary artery disease in reference to invasive coronary angiography and nuclear myocardial perfusion imaging using SPECT. The study included 381 patients, 229 with obstructive coronary artery disease. The results indicated that identifying patients with inducible myocardial ischemia by SPECT was similar for both CTA and invasive coronary angiography.  “Contemporary CTA accurately identifies patients with obstructive CAD by ICA at lower radiation exposure; however, agreement is lower in vessel- and segment-level analyses,” the researchers wrote. “Both CTA and ICA perform similarly for predicting clinically driven revascularization and for detecting myocardial ischemia by myocardial perfusion imaging using SPECT, suggesting that limitations by both CTA and invasive coronary angiography contribute to variability of stenosis quantification.”

Read more in Circulation Cardiovascular Imaging: https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.118.007720