Weight Loss Could Result in T2D Remission

Behavioral change and weight loss could help patients diagnosed with type 2 diabetes (T2D) achieve remission, according to a new study. Here, researchers examined 867 newly diagnosed T2D patients aged between 40 and 69 years from the ADDITION-Cambridge trial. Baseline and one-year assessments included weight change, physical activity (EPAQ2 questionnaire), diet (plasma vitamin C and self‐report), and alcohol consumption (self‐report). Five-year remission was evaluated via HbA1c level. At five-year follow-up, 257 patients (30%) had achieved remission. Compared to patients who maintained their weight during the study period, those who lost at least 10% of their weight in the year following their diagnosis were significantly more likely to achieve remission. During the five-year period following diagnosis, achieving at least a 10% weight loss was also significantly associated with remission. There were no consistent findings in terms of unit changes in health behaviors and diabetes remission. There was a positive correlation between remission and unit changes in alcohol levels, but these findings were not consistent across unadjusted and adjusted models.

Source: Dambha-Miller H, Day AJ, Strelitz J, et al. Diabet Med. 2019;doi: 10.1111/dme.14122