Effect of HIIT on LVSV in Diabetic Adults

Patients with type 2 diabetes mellitus (T2DM) could improve their left ventricular stroke volume (LVSV) response to exercise by engaging in high-intensity interval training (HIIT), according to a study published in the June issue of Medicine & Science in Sports & Exercise. A total of 16 patients underwent a baseline DXA scan and total blood volume measurement and performed V˙O2peak test. For three months, patients either participated in HIIT (n = 11) or no training (control, n = 5); researchers measured left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), and left ventricular stroke volume (LVSV) at baseline and after three months. HIIT resulted in an approximate 15 percent increase in V˙O2peak, but body composition and total blood volume were not affected. Baseline LVESV decreased and LVEDV and LVSV increase in both groups from rest to moderate-intensity exercise. After three months, HIIT was associated with an increase in LVEDV and LVSV at all conditions, and an increased reduction in LVESV from rest to moderate-intensity exercise. The control group had no differences in LVEDV, LVSV, or LVESV.

Source: Wilson GA, Wilkins GT, Cotter JD, et al. Med Sci Sports Exerc. 2019;doi: 10.1249/MSS.0000000000001897