Study Unable to Rule Out Link Between TNF Inhibitors and Cancer Risk
A study published in the Annals of Internal Medicine found that treatment with tumor necrosis factor TNF inhibitors is not associated with increased risk for cancer recurrence in patients with rheumatoid arthritis (RA); however, the researchers said, “meaningful risk increases could...
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This Week`s Featured Journal: ASH Clinical News
Latest ASH Clinical News Articles
Today`s Top 5
5. Will CAR T Replace Chemo?
Could CAR T-cell therapy replace #chemo and #stemcelltransplants? Our expert Dr. Sattva Neelapu weighs in: https://t.co/QXABGqBenQ #endcancer pic.twitter.com/NJ603suvx4
— MD Anderson Cancer Center (@MDAndersonNews) August 10, 2018
4. Ethics in Clinical Trials
Ethics and the underreporting of research biopsies in #clinicaltrials. Learn more https://t.co/Dx8ped68WX
— JAMA Oncology (@JAMAOnc) August 11, 2018
3. Lung Cancer Screening Shared Decision-Making
#LungCancer screening shared decision making not up to par, found researchers from @UNC_SOM: https://t.co/6HJKbxpzMY #primarycare pic.twitter.com/woNZFwLyon
— Healio Internal Med (@HealioIM) August 13, 2018
2. Clinical Trial Questions
Two Q’s I ask about all #clinicaltrials: 1) is the treatment effect size being targeted clinically meaningful? 2) is the minimum treatment effect size that would produce a statistical “win” clinically meaningful? Make them both yes & everyone has a better day.
— Tatiana Prowell, MD (@tmprowell) August 13, 2018
1. Presumption of NGS Benefit?
Sorry, no. Value of NGS is entirely a fxn of freq of markers, whether 1 or many, w/effective Rx. If you have 2-3 markers w/good Rx at 1% freq, NGS won't prove beneficial. If 8 at 1-10% freq each, it will. I'm increasingly sold based on data but don't accept presumpt'n of benefit. https://t.co/O4cbk22bHV
— H. Jack West, MD (@JackWestMD) August 14, 2018
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