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This Week`s Featured Journal: ASH Clinical News
Latest ASH Clinical News Articles
Today`s Top 5
5. Will CAR T Replace Chemo?
4. Ethics in Clinical Trials
3. Lung Cancer Screening Shared Decision-Making
2. Clinical Trial Questions
Two Q’s I ask about all #clinicaltrials: 1) is the treatment effect size being targeted clinically meaningful? 2) is the minimum treatment effect size that would produce a statistical “win” clinically meaningful? Make them both yes & everyone has a better day.— Tatiana Prowell, MD (@tmprowell) August 13, 2018
1. Presumption of NGS Benefit?
Sorry, no. Value of NGS is entirely a fxn of freq of markers, whether 1 or many, w/effective Rx. If you have 2-3 markers w/good Rx at 1% freq, NGS won't prove beneficial. If 8 at 1-10% freq each, it will. I'm increasingly sold based on data but don't accept presumpt'n of benefit. https://t.co/O4cbk22bHV— H. Jack West, MD (@JackWestMD) August 14, 2018