According to a study published in Cancer, postmenopausal women who lose weight have a lower risk of breast cancer compared with those with a stable weight.
The researchers assessed 61,335 postmenopausal women who had no prior breast cancer and a normal mammogram. They calculated body mass index at baseline and at 3 years, categorizing participants as having a weight change of stable (<5%; n=41,139), loss (≥5%; n=8,175), or gain (≥5%; n=12,021).
— Bariatric News (@BariatricNews) October 9, 2018
During a mean follow‐up of 11.4 years, there were 3,061 incident breast cancers.
Women who lost weight had a 12% lower risk of breast cancer compared with women whose weight was stable (hazard ratio [HR] = 0.88; 95% CI, 0.78‐0.98; P=0.02). Among women who gained weight, there was no observed association with breast cancer risk (HR=1.02; 95% CI, 0.93‐1.11); however, weight gain was associated with a higher incidence of triple‐negative breast cancer (HR=1.54; 95% CI, 1.16‐2.05).
“These findings suggest that postmenopausal women who lose weight may reduce their breast cancer risk,” the researchers concluded.