Cardio Round-Up: High-Density Lipoprotein Peroxidation as a Predictive Biomarker in Coronary Artery Disease

High-Density Lipoprotein Peroxidation as a Predictive Biomarker in Coronary Artery Disease

Researchers, led by Shima Yazdandoust, sought to uncover associations between high-density lipoprotein lipid peroxidation (HDLox) levels and coronary artery disease (CAD) via coronary angiography. Their study, published in Biofactors, found that the oxidation of high-density lipoprotein (HDL) “leads to a reduction in its antioxidant function,” and plays a significant role in the development of atherosclerosis.

Peritoneal Dialysis in Heart Failure

The researchers conducted a review of the contemporary evidence of the use of peritoneal dialysis in patients with heart failure and diuretic resistance across the spectrum of ventricular dysfunction and degree of renal dysfunction. The review is reported in Reviews in Cardiovascular Medicine, 2021;22(3):649-657.

Risk for Cancer Increased After VTE for Patients With Psoriasis

For patients with psoriasis, the risk for cancer is increased at the time of or after venous thromboembolism (VTE), according to a research letter published online Jan. 18 in the British Journal of Dermatology.

“At the time of VTE or in the first year afterwards, we found a clearly increased cancer risk in patients with psoriasis,” the authors write. “Comprehensive research has shown that extensive screening for occult cancer in patients with VTE in general will lead to a higher rate of cancer detection, but these strategies have not been associated with improved cancer related mortality.”

Plasma Micro RNA-1-3p Levels Linked to Development of Atrial Fibrillation

Researchers, led by Begoña Benito, MD, from the Hospital Universitari Vall d’Hebron in Barcelona, Spain, examined markers of subclinical atrial fibrillation (AFib) in patients with cryptogenic stroke (CrS) by comparing circulating microRNA (miRNA) profiles between patients with CrS and AFib and those with persistent sinus rhythm. The study, published in Revista Española de Cardiologia, reported that plasma levels of miR-1-3p were elevated in patients with CrS and subsequent AFib.