Here are the top stories covered by DocWire News this week in the Hematology & Oncology section. This week, a study found that exposure to germs early in life reduces the risk of leukemia, a novel drug improved survival for patients with stomach cancer, and more.
A study published in Nature Reviews Cancer found that a lack of exposure to germs early in life, followed by an infection, increases the risk for childhood leukemia. The study found that when a baby is exposed to infections during its first year, the immune system is strengthened. But when the child experiences later infections, without the initial exposure to germs, leukemia can be triggered in those with the genetic predisposition.
Topline results from the pivotal phase III INVICTUS trial showed that the novel drug ripretinib improved progression-free survival (primary endpoint) compared with placebo in patients with gastrointestinal stromal tumors, according to a press release from the drug’s manufacturer.
The chimeric antigen receptor T-cell therapy tisagenlecleucel showed measurable in vivo expansion in patients with relapsed/refractory diffuse large B-cell lymphoma who had no measurable disease after bridging therapy, according to a study published in Blood Advances.
A study published in Blood found that having a parent, sibling, or child with blood cancer increases a person’s likelihood of being diagnosed with the disease. The majority of hematological malignancies showed increased familial relative risks (FRRs) for the same tumor type, with the highest FRRs observed for mixed cellularity Hodgkin lymphoma, lymphoplasmacytic lymphoma, and mantle cell lymphoma.
Psychiatric disorders and stressful life events that occur around a cervical cancer diagnosis are associated with increased cancer-specific mortality, independent of tumor characteristics and treatment modality, according to a study published in Cancer Research.
In case you missed it, more hem/onc headlines are featured below:
- Rogaratinib Exhibits Efficacy in the Treatment of Advanced Cancer
- Can a Multiple Sclerosis Drug Be Used to Treat Brain Cancer?
- New Pancreatic Cancer Drug Shows Promise in Clinical Trial
- Nurse Who Tampered with Medication Left Six Cancer Patients with Rare Blood Infection: Report
- Aspirin Use Prior to Breast Cancer Diagnosis Improves Survival in Certain Women
- Study Compares Skin Cancer Treatments, Finds Mohs Micrographic Surgery and Brachytherapy Improve Cosmesis
- Researchers Identify a Gene Mutation that Increases the Risk of Pancreatic Cancer
- First U.S. Patient Receives CRISPR Gene Therapy for Sickle Cell Disease
- Young Colorectal Cancer Patients Are Going Undiagnosed
- CAR T-Cell Cancer Therapy Will Be Covered by Medicare
- How Does Preventative Oophorectomy Affect Bone Health?
- Combination Therapy for Melanoma May Increase Cardiovascular Risks
- Could Race Delay, Extend Breast Cancer Treatment?
- Can A New Test Better Predict Cervical Cancer in HPV-Positive Women?