Diabetes is an Independent Predictor for Heart Failure

Diabetes mellitus is an independent predictor for heart failure, according to the findings of a study published in Mayo Clinic Proceedings.

In this study, using the Rochester Epidemiology Project, researchers assessed the long-term impact of diabetes on the development of heart failure by including 116 study subjects with diabetes, who were matched 1:2 based on age, hypertension, sex, coronary artery disease and diastolic with 232 participants without diabetes. The researchers also looked at mortality rates in the study population while controlling for hypertension, coronary artery disease and diastolic function.

Following analysis, the results showed that that diabetes is an independent risk factor for the development of heart failure. Over the duration of 10 years, 21% of participants with diabetes developed heart failure, independent of other causes. The researchers observed that by comparison, only 12% of patients without diabetes developed heart failure. They also found that cardiac death, heart attack and stroke were not statistically different in the study between the two groups.

This research builds upon previous findings and demonstrates that even without a known cardiac abnormality and with a healthy ejection fraction, diabetic patients still incur an increased risk of heart failure compared to those without the disease.

“The key takeaway is that diabetes mellitus alone is an independent risk factor for the development of heart failure,” says Horng Chen, MD, cardiologist at Mayo Clinic in Rochester, Minnesota, is senior author of the study in a press release. “Our hope is that this study provides a strong foundation for further investigations into diabetes and heart failure. There is still much to learn and study in terms of this association and how to best diagnose and treat this condition.”