Cardio Round-Up: Interview Regarding Important Findings; and More

Dr. Jay Matthews On New Data that Demonstrate the Safety and Efficacy of Continuous Aspiration Thrombectomy

Recently, the CHEETAH study (initiated in 2019), the first large study to demonstrate the safety and performance of continuous aspiration thrombectomy for high-risk patients with significant blood clots in the heart.

DocWire News spoke to S.Jay Matthews, MD, MS, and principal investigator of the study, about the findings of this study and its implications.

Transaxillary Approach With Prosthetic Conduit in Transcatheter Aortic Valve Replacement

The left subclavian artery (LSA) is an alternative access path for patients with severe peripheral artery disease (PAD), though it is not frequently used. Researchers, led by Alexander Lind, evaluated a new approach that combined “an axillary prosthetic conduit-based access technique with new-generation balloon-expandable [transcatheter aortic valve replacement (TAVR)] prostheses.” The collaborators’ report, published in Frontiers in Cardiovascular Medicine, stated that the approach technique allowed for safe and successful TAVR in a subgroup of patients with a high risk of procedural complications due to severe peripheral vascular disease.

Left Atrial Appendage Closure Devices and Direct Oral Anticoagulants in Atrial Fibrillation

According to a study published in Cardiovascular Intervention and Therapeutics, the safety and efficacy profiles of left atrial appendage closure devices (LAAC) in patients with atrial fibrillation (AFib) are lacking research. Investigators, led by Keiichi Takeda, examined all-cause mortality, stroke, major bleeding, medications, and device-related thrombus (DRT) in patients with AFib managed with a LAAC device and direct oral anticoagulants (DOACs).

According to their report, “the incidence of all-cause mortality, stroke, and major bleeding were similar between LAAC devices and DOACs.” Furthermore, Takeda and colleagues stated that “the rate of complications was acceptable, and those of DRT were lower than the average incidence reported in previous studies.