Cardio Round-Up: The Impact of Successful Pig-to-Human Heart Transplants; and More

Serum Magnesium and Risk of Cardiovascular Events

In the general population there are associations between hypomagnesemia and cardiovascular events and between hypermagnesemia and overall mortality. However, according to Isabel Galán Carrillo, MD, and colleagues, the data in patients with chronic kidney disease (CKD) are not as strong. The researchers conducted an observational study to examine the relationship between serum magnesium (SMg) concentration and cardiovascular morbidity and mortality, all-cause mortality, and progression to kidney failure in a population of patients with CKD. Results were reported in the Journal of Renal Nutrition.

Short-Term Outcomes of TurboHawk Atherectomy for In-Stent Restenosis in Peripheral Artery Disease

Researchers, led by Yi Qin, MD, investigated the use of the TurboHawk atherectomy in the treatment of in-stent restenosis (ISR) in patients aged 60 years or more with peripheral artery disease (PAD) in the lower extremity. Their study, published in ANZ Journal of Surgery, reported favorable safety and efficacy profiles for the TurboHawk device.

The trial was conducted on a total of 28 patients with PAD and ISR at the authors’ center. Based on the short-term data from their operations and follow-up, the study’s authors concluded that the TurboHawk atherectomy appears to be a safe and effective surgical technique for the treatment of in-stent restenosis in patients with PAD.

P Wave Peak Time on Surface ECG Predicts Post-Operative Atrial Fibrillation

Researchers, led by Ahmet Zengin, MD, from the Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center in Üsküdar/Istanbul, Turkey, evaluated a newly developed electrocardiography (ECG) parameter, P wave peak time (PWPT), as a predictor for post-operative atrial fibrillation (AFib) in patients undergoing cardiac surgery. Their study, published in the Irish Journal of Medical Science, reported that “PWPT in leads DII and V1 can predict the development of [post-operative AFib] in patients undergoing cardiac surgery.”

Xenotransplantation: Successful Pig-to-Human Heart Transplantation Highlights the X-Factor in the Treatment of Advanced Heart Failure

In a medical breakthrough, the first genetically-engineered porcine heart was transplanted into a 57-year-old patient at the University of Maryland on January 7, 2021 by Dr. Bartley Griffith and his surgical team. The patient is currently awake, breathing on his own, and successfully weaned off of mechanical circulatory support.

Find about more about the breakthrough that is xenotransplantation.