Cardio Round-Up: Beware of Heart Hazards Amid Winter Season; and More

Shoveling Snow? Beware of Heart Hazards

Shoveling snow can cause heart attacks or sudden cardiac arrest in folks with heart conditions and even in those who are unaware that they have heart disease, the American Heart Association (AHA) warns.

“Shoveling snow is a very strenuous activity, made even more so by the impact that cold temperatures have on your body, increasing the blood pressure while simultaneously constricting the coronary arteries. It really is a ‘perfect storm’ for acute cardiac events,” Barry Franklin said in an AHA news release. He is the lead author of an AHA scientific statement on exercise-related heart risks.

Sex Hormone-Binding Globulin May Be Biomarker for CVD Risk in Men

Men with lower concentrations of total testosterone do not have an increased risk for cardiovascular events, while lower concentration of sex hormone-binding globulin (SHBG) is associated with a higher incidence of myocardial infarction (MI), according to a study published online Dec. 28 in the Annals of Internal Medicine.

Bu B. Yeap, Ph.D., from the University of Western Australia in Perth, and colleagues examined the associations of serum total testosterone and SHBG with incident cardiovascular events among community-dwelling men ages 40 to 69 years from the U.K. Biobank prospective cohort.

AI Algorithm Can Predict 10-Year Death Risk in CAD Patients

A machine learning (ML) score based on clinical data and stress cardiovascular magnetic resonance (CMR) measurements can predict 10-year all-cause mortality in patients with known or suspected coronary artery disease (CAD), according to a study presented at EuroEcho 2021, a scientific congress of the European Society of Cardiology, held from Dec. 9 to 11 in Berlin.

Complete Revascularization Optimizes Patient Outcomes in Multivessel Coronary Artery Disease: Data from the e-Ultimaster Registry

Researchers, led by Timothy Williams, MD, from the Sussex Cardiac Centre at the Brighton and Sussex University Hospitals, examined the impact of the coronary revascularization strategy during admission on outcomes in patients with multivessel coronary artery disease (MVD) undergoing percutaneous coronary intervention (PCI). Their report, published in Catherization and Cardiovascular Interventions, found that a physician-directed CR strategy including sirolimus-eluting thing-strut stents appeared to result in more optimal clinical outcomes and less angina.

According to Dr. Williams, “Our findings suggest that a CR should be aimed for.” The researchers investigated 15,441 patients with MVD, defined as two or more major epicardial vessels with ≥50% stenosis, from the observational all-comer e-Ultimaster registry. The degree of revascularization achieved was assessed by a physician at the index procedure or a later procedure during hospitalization. The primary outcomes were complete revascularizations (CR), incomplete revascularizations (IR), target lesion failure (TLF), and patient-oriented composite outcome (POCE).

Electrical Cardioversion Procedure: Risk of Acute Ischemic Stroke in Atrial Fibrillation

Four weeks of anticoagulation therapy after an electrical cardioversion procedure (ECV) in patients with atrial fibrillation (AF) is suggested by current guidelines to reduce the risk of stroke. However, according to a study published in the International Journal of Cardiology, there is a lack of recent data on acute ischemic stroke (AIS) risk and timing after ECV for AF.

The team reviewed data of patients from the National Health Insurance Research Database (NHIRD) in Taiwan. Their final cohort included 5,723 patients with AF who received an ECV procedure and 5,723 propensity score-matched controls. The primary outcome assessed was the cumulative incidence of AIS during the two follow-up periods listed above.

Compared to the controls, patients with AF who received an ECV procedure demonstrated a significantly increased incidence of seven-day AIS development (adjusted hazard ratio [HR] = 1.524; p = 0.003). However, the increase was not significant at day 30 (HR = 1.301; p = 0.426).