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Prevalence of GVHD in Patients With B-Cell Malignancies Receiving Allogeneic CAR T-Cells

In a meta-analysis presented at the 2022 American Society of Clinical Oncology Annual Meeting, researchers evaluated allogeneic chimeric antigen receptor (CAR) T-cell therapy in...
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GVHD Prophylaxis Well-Tolerated in Patients With PTCL Undergoing Transplant

According to research presented at the 2022 American Society of Clinical Oncology Annual Meeting, graft-versus-host disease (GVHD) prophylaxis with post-transplant cyclophosphamide—as well as mycophenolate...
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GVHD Is Less Common in Hispanic Patients With MPN Than Non-Hispanic White Patients

Hispanic patients had a significantly lower cumulative incidence of chronic graft-versus-host disease (GVHD) than non-Hispanic White patients in a retrospective analysis of those with...
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No GVHD Reported in First-in-Human Trial of ADI-001 CAR-T for Relapsed/Refractory Advanced B-Cell Lymphoma

The first-in-human, phase I clinical trial of ADI-001, an allogeneic gamma delta chimeric antigen receptor (CAR) T-cell therapy, in relapsed/refractory advanced B-cell lymphoma established...
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Literature Review Assesses Use of Ruxolitinib in Chronic Steroid-Refractory GVHD

A study presented at the 2022 American Society of Clinical Oncology Annual Meeting reported on results of a literature review compiling outcomes of ruxolitinib...

Chronic GVHD Incidence Significantly Lower in Patients With HLA-Matched Donors Than Haploidentical Donors

Patients who received an allogeneic hematopoietic stem cell transplant (HSCT) from matched related donors (MRD) or matched unrelated donors (MUD) had a significantly lower...
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CAR T-Cell Therapy Appeared Safe, With No Signs of GVHD in Patients With T-Cell...

A study presented at the 2022 American Society of Clinical Oncology Annual Meeting found that an autologous CD7 chimeric antigen receptor (CAR) T-cell therapy...

Mismatched Donor Transplantation Associated With Minimal GVHD in Cutaneous T-Cell Lymphoma

A retrospective study found that partially mismatched blood or marrow transplantation with post-transplantation cyclophosphamide resulted in minimal graft-versus-host disease (GVHD) and improved survival in...

ASCO 2022

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