Tricuspid Regurgitation after Permanent Pacemaker Implantation Develops Regardless of Structural Heart Disease

This study looking at tricuspid regurgitation (TR) after permanent pacemaker implantations and its influence on atrial fibrillation (AF), included 530 patients with dual-chamber permanent pacemakers. Primary outcomes included moderate to severe tricuspid regurgitation and isolated tricuspid regurgitation. Median follow-up was 7.6 years. Multivariable analysis revealed independent predictors of moderate to severe TR, including diabetes, chronic lung disease, pre-existing mild tricuspid regurgitation, peripheral artery disease, moderate to severe aortic regurgitation, and persistent AF. Persistent AF was associated with a higher incidence of moderate to severe TR (21.8% vs. 12.9% vs. 11.6% for persistent AF, paroxysmal AF and without AF, respectively).


Cho M, Kim J, Lee J, et al. Pacing Clin Electrophysiol. 2018;doi:10.1111/pace.13543