ORBIT-AF Analysis: Systolic BP Linked with Increased Events in AFib

This study looked at systolic blood pressure (BP) and it’s relationship with clinical outcomes in patienst with atrial fibrillation (AFib). The study included over 10,000 patients with AFib from the ORBIT-AF Registry. The authors used Cox regression models to compare cardiovascular outcomes and major bleeing. The results showed that for every 5 mm Hg increase in follow-up systolic BP, the risk for stroke/systemic embolism, transient ischemic attack, myocardial infarction, and major bleeding increased modestly. The authors said that “more rigorous blood pressure control should be emphasized.”

Vemulapalli S, Inohara T, Kim S, et al. Am J Cardiol. 2019;doi:10.1016/j.amjcard.2019.02.010