The Clinical Significance of New-onset Atrial Fibrillation after TAVI

Researchers for this paper evaluated 347 consecutive patients from the ASAN-TAVI Registry who underwent transcatheter aortic valve implantation (TAVI) for severe aortic stenosis, with a primary endpoint of stroke or systemic embolism at 12 months. The patient groups consisted of pre-existing atrial fibrillation (AF; 50 patients), new-onset AF (31 patients), and no AF (266 patients). New-onset AF was associated with an increase in the 1-year primary endpoint and was an independent predictor of 1-year mortality. The researchers concluded that “patients with severe AS undergoing TAVI, new-onset AF occurred in 10% and 1 of 4 new-onset AF patients experienced stroke or systemic embolization.” The presence of new-onset AF, they wrote, “was associated with a substantially higher risk of stroke or systemic embolization.”


Yoon YH, et al. Am J Cardiol. 2019;doi:10.1016/j.amjcard.2018.12.041