Stroke and Bleeding Risk Scores in AF Patients and Valvular Heart Disease

This paper was a nationwide cohort study of stroke and bleeding rates in patients with atrial fibrillation (AF) and valvular heart disease when compared to CHA2DS2-VASc and HAS-BLED scores. The study included 25,818 patients with AF, 90% of whom had EHRA Type 2 valvular heart disease. According to the results, the predictive values of both CHA2DS2-VASc and HAS-BLED were described as “modest” at one year for EHRA Type 1 outcomes and was also reported as modest for EHRA Type 2 outcomes. “This is the first validation of CHA2DS2-VASc and HAS-BLED scores in AF patients with VHD (so-called ‘valvular AF’) using the new EHRA classification,” the researchers wrote. “Both scores are modestly predictive of thromboembolism and bleeding events in VHD, respectively.”


Lip GY, et al. EP Europace. 2019;doi:10.1093/europace/euy151