Many middle-aged adults with apparently healthy hearts have a “silent” buildup of fatty deposits in their arteries, a large, new study shows. Researchers found that of more than 25,000 50- to 64-year-olds, about 42% had signs of atherosclerosis — a buildup of “plaques” in the arteries that can lead to a heart attack or stroke. “It’s a really important study because of the representative population,” said Dr. Donald Lloyd-Jones, president of the American Heart Association. “Forty-two percent of people in this age group do indeed have some plaques in their arteries. And it’s important to focus attention on that.”
A study finds that there is an augmented risk of venous thromboembolism (VTE) after acute ischemic stroke (AIS), and this risk among patients treated with intravenous thrombolysis (rtPA). The findings were published in the Journal of Stroke and Cerebrovascular Diseases. According to the results, hospitalizations due to AIS had increase of VTE as juxtaposed to the controls [OR=1.50, 95% CI, 1.40-1.60, P<0.001].
A study finds that lipid-lowering therapy is associated with a significant reduction in major adverse limb events (MALE), which has important clinical implications for patients with peripheral artery disease (PAD) who are at increased risk of MALE. This meta-analysis focused on identifying randomized studies that evaluated the use of lipid-lowering therapy in patients with PAD and reported MALE. The researchers demonstrated that hat lipid-lowering therapy was associated with a lower incidence of MALE (OR=0.76, 95% confidence interval: 0.66-0.87; I2: 28%) compared to placebo/control groups. A subsequent sensitivity analysis backed the findings as clinically robust.
The findings of a recent study indicate that women with atrial fibrillation (AFib) have worse quality of life compared to men with AFib. The results appeared in the American Journal of Preventative Cardiology. According to the results, women with AFib reported worse physical functioning, social functioning, and mental health compared to their male counterparts. These differences were attenuated with adjustment for comorbid conditions and depression, the researchers noted.