Can f 5 as a suitable marker of dog allergy: Assess male dog exposure before banning it

This article was originally published here

We read with interest the excellent article by Käck et al1 focusing on the role of different dog allergens in inducing nasal symptoms as assessed by nasal provocation tests (NPTs). It is well known that a significant percentage of individuals sensitized to dog allergens by skin prick tests do not develop overt respiratory symptoms (asthma and/or rhinitis) after direct dog exposure. For this reason, NPTs can be regarded as the “criterion standard” to clarify whether a sensitization to dog allergens can be regarded clinically relevant.