Testicular sarcoidosis with bilateral scrotal swelling

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IJU Case Rep. 2019 Oct 19;3(1):12-14. doi: 10.1002/iju5.12124. eCollection 2020 Jan.


INTRODUCTION: Sarcoidosis is a disease in which noncaseating granulomas form in several organs, particularly in the lungs and skin. Male genitourinary involvement in sarcoidosis is uncommon.

CASE PRESENTATION: A 32-year-old male with painless bilateral scrotal swelling who was diagnosed with lung sarcoidosis presented to our hospital. Serum tumor marker levels were normal. Scattered hypoechoic mass lesions in both testes were noted on ultrasound examination. Biopsy of both testes revealed pathologically noncaseating epithelioid cell granuloma, and perihilar lymphadenopathy and a granulomatous lung nodule were found on chest computed tomography. Semen examination was performed after the biopsy, demonstrating oligospermia. A corticosteroid regimen was administered. After treatment, no abnormal accumulation in both testes was observed on gallium-67 scintigraphy, and semen examination demonstrated the mild improvement of the sperm count.

CONCLUSION: Treatments for testicular sarcoidosis vary, and malignancy and fertility must be considered.

PMID:32743456 | PMC:PMC7292101 | DOI:10.1002/iju5.12124