Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave

This article was originally published here

Clin Infect Pract. 2022 Jan 3:100131. doi: 10.1016/j.clinpr.2021.100131. Online ahead of print.

ABSTRACT

INTRODUCTION: Asymptomatic COVID-19 patients are the most challenging and feared obstacles in resuming these surgical procedures. The purpose of this study was to evaluate the proportion of asymptomatic carries detected by RT-PCR in pre-operative orthopaedic evaluation during the peak of the second wave.

METHODS: 514 asymptomtomatic COVID-19 patients, negative for TOCC (Travel, Profession, Cluster, Contact) risk factors were observed retrospectively. A nasopharyFngeal RT-PCR test was obtained 48 to 72 hours before the surgery in all cases. Possible risk factors for a positive test was identified.

RESULTS: The detected asymptomatic COVID-19 infection rate during the peak of the second wave among the pre-operative orthopaedic patients was 12.3%. Younger age, female gender, longer duration of admission to RT-PCR test interval were found to be significant (p= < .05) risk factors for asymptomatic RT-PCR to be positive. The hazard ratio (HR) for being asymptomatic RT-PCR positive was 4.3 (p = 0. 025), while the RT-PCR was performed at 14 days, but the HR increased to 9.2 (p = 0.049) when the test was performed after 45 days.

CONCLUSION: According to our findings, pre-operative testing to rule out COVID-19 should be regarded as a critical step in preventing the disease clusters in hospitals.

PMID:35005607 | PMC:PMC8721921 | DOI:10.1016/j.clinpr.2021.100131