Uncovering Mitochondrial Determinants of Racial Disparities in Ovarian Cancer

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Trends Cancer. 2020 Nov 24:S2405-8033(20)30288-0. doi: 10.1016/j.trecan.2020.10.014. Online ahead of print.

ABSTRACT

Ovarian cancer (OC) incidence and mortality rates differ between racial groups. Mitochondrial genetic factors are now emerging as determinants of racial disparities in OC. A comprehensive understanding of the role of mitochondria in OC health disparities will help in developing novel therapeutic strategies targeting mitochondria to reduce or eliminate racial health disparities.

PMID:33246874 | DOI:10.1016/j.trecan.2020.10.014