Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report

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Neurol Sci. 2021 Apr 16. doi: 10.1007/s10072-021-05233-y. Online ahead of print.


We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.

PMID:33864172 | DOI:10.1007/s10072-021-05233-y