Diagnostic protocol for chronic manifestations of COVID-19

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Medicine (Madr). 2022 May;13(55):3256-3260. doi: 10.1016/j.med.2022.05.007. Epub 2022 May 12.


Many people who have had COVID-19 continue to have symptoms weeks and months after recovering from the acute disease. They present with a highly heterogeneous set of manifestations whose pathophysiology is unknown. There is no uniform nomenclature or agreed-upon diagnostic criteria. One of the main risk factors for its onset is having required intensive care unit admission. The most common manifestations are fatigue and respiratory symptoms, of note among which is dyspnea. The diagnostic approach is focused on ruling out other possible causes that could be responsible for said manifestations. Therefore, a comprehensive evaluation of the patient is conducted followed by a later approach aimed at the nonspecific symptoms.

PMID:35582695 | PMC:PMC9097968 | DOI:10.1016/j.med.2022.05.007